3.2.S.1.3 - General Properties

A list of and other relevant properties of the active substance should be provided, in particular physico-chemical properties that affect the efficacy and safety of the drug products, such as:

  • Solubility;
  • pKa;
  • Polymorphism;
  • Isomerism;
  • Partition coefficient (logP);
  • Permeability;
  • Hygroscopicity.